2021. 2021.2. 28. Ishikawa group moved to Chiba University.
      

                                         (Graduate School of Pharmaceutical Sciences)

                     Home Page at Chiba University

2021. 2. 10. Our recent work; accepted in Scientific Reports

                    Discovery, Characterization and Functional Improvement of Kumamonamide as a Novel

                    Plant Growth Inhibitor that Disturb Plant Microtubules

                    Takashi Ishida*, Haruna Yoshimura, Masatsugu Takekawa, Takumi Higaki, Takashi Ideue,

                    Masaki Hatano, Masayuki Igarashi, Tokio Tani, Shinichiro Sawa, Hayato Ishikawa*

　　　　　 Sci. Rep. DOI:10.1038/s41598-021-85501-1

2020. 5. 1.  Our recent work accepted in Angewandte Chemie, International Edition.

                    Total Syntheses of (–)-Strictosidine and Related Indole Alkaloid Glycosides

                     Jukiya Sakamoto, Yuhei Umeda, Kenta Rakumitsu, Michinori Sumimoto,Hayato Ishikawa*

                    Angew. Chem., Int. Ed., 59, 13414–13422 (2020).

2020. 4. 1. New member join our group!

2019. 12. 30. Our recent work published in Organic Letters.

                       Diaryliodonium Salt-Mediated Intramolecular C–N Bond Formation Using Boron-Masking

                       N-Hydroxyamides.

                       Makoto Matsumoto, Kohei Wada, Kazuki Urakawa, Hayato Ishikawa*

                       Org. Lett. 22, 781–785 (2020).

                       Selected “Cover Picture”

2019. 2019.12. 30. Our recent work published in Molecular Plant.
      

                      Identification of Naturally-Occurring Polyamines as Nematode Meloidogyne incognia

                      Attractants

                      Morihiro Oota, Allen Y.-L. Tsai, Dan Aoki, Yasuyuki Matsushita, Syuuto Toyoda,

                      Kazuhiko Fukushima, Kentaro Saeki, Kei Toda, Laetitia Perfus-Barbeoch, Bruno Favery,

                      Hayato Ishikawa*, Shinichiro Sawa*

                     Mol. Plant 13, 658–665 (2020)

2019. 12. 6. Visiting scientist Ms. Listiana Oktavia (from Indonesian Institute of Science, Indonesia)

                      join our group.

2019. 11. 29. Update photos.

2019. 11. 29. Our research group awarded best promotion award in Science Festa 2019 for Students!

                 （夢科学探検2019で優秀な展示をしたグループに送られる化血研大賞を受賞しました！）

2019. 11. 29. Kenta Rakumitsu awarded best poster presentation award  in 9th. CSJ  Festa!

                     (The Chemical Society of Japan).

2019. 11. 7. Our quinine synthesis was highlighted by “Chemistry World (RSC)”.

                    We appreciate very kind comments in "Chemistry World" from Prof. Maulide

                    and Prof. Stockdill!

2019. 9. 20. Our recent work published in Chemical Science.

                     Total Synthesis of the Unnatural Enantiomer of Quinine.

                     Shinya Shiomi, Remi Misaka, Mayu Kaneko, Hayato Ishikawa*

                     Chem. Sci. 10, 9433–9437 (2019).

                     Selected “2019 Chemical Science HOT Article Collection” and”Inside Front Cover”

　　　　　  Highlighted in “Chemistry World” and “ChemistryViews”

2019. 5. 27. Kenta Rakumitsu awarded Best Poster Presentation Award in

                    29th Banyu–Fukuoka Symposium!

2019. 5. 9. Our recent work published in Chemistry A European Journal.

                 Total Syntheses of (–)-Secologanin, (–)-5-Carboxystrictosidine, and (–)-Rubenine.

                  Kenta Rakumitsu, Jukiya Sakamoto, Hayato Ishikawa*

                  Chem. Eur. J., 25, 8996–9000 (2019).

2019. 4. 11. Update photos.

2019. 4. 6. Our recent work published in Organic Letters.

                 Enantioselective Construction of Octahydroquinolines via Trienamine-Mediated Diels-Alder

                 Reactions.

                  Taichi Inoshita, Kei Goshi, Yuka Morinaga, Yuhei Umeda, Hayato Ishikawa*

                  Organic Letters, 21, 2903－2907(2019).

2019. 4. 1. New member join our group! 

2018. 10. 9. Our research topics adopted by THE NAITO FOUNDATION

2018. 10. 6. Update photos

2018. 10. 1. Dr. Ishikawa promote to full professor

2018. 5. 7. Update photos and completed project

2018. 4. 14. Our recent work published in Organic Letters

                    It is collaborative work with Prof. Sumimoto who is specialist of computational chemistry.

                   α-Ketocarbenium Ions Derived from Orthoquinone-Containing Polycyclic Aromatic

                   Compounds.

                   Kazuki Urakawa, Yuta Kawabata, Masaki Matsuda, Michinori Sumimoto*, Hayato Ishikawa*

                  Organic Letters, 20, 2534–2537 (2018).

2018. 4. 5.  Update photos

2018. 4.1.  New member join our group!

2018. 2. 16. Our recent Book Chapter was disclosed!

                    Alkaloid Synthesis using Organicatalysts

                    Hayato Ishikawa*, Shinya Shiomi

                    The Alkaloids, Elsevier, Vol79, pp1–70 (2018).

2018. 2. 10. update photos

2018. 2. 3. Our recent work published in Bioorganic & Medicinal Chemistry Letters

                   It is belongs to special issue “Prof. Dale L. Boger: A Celebration of 65 Years of Excellence”

                   Congratulation! Prof. Boger!

                   Total Syntheses and Stereochemical Reassignments of Mollenines A and B

                   Shinya Shiomi, Kohei Wada, Yuhei Umeda, Hikaru Kato, Sachiko Tsukamoto,

                   Hayato Ishikawa*

                   Bioorg. Med. Chem. Lett. 28, 2766–2769 (2018).

2018. 1. 16.  update publication list

2017. 8. 15.  Our recent work published in Journal of Natural Products

                      Bioinspired Indole Prenylation Reactions in Water

                      Satomi Tanaka, Shinya Shiomi, Hayato Ishikawa*

                      J. Nat. Prod., 80, 2371–2378 (2017).

                      Selected ACS Editors Choice and “most accessed article in 2017 ranked 7th”

2017. 4. 1. New member join our group!

2016. 12. 21. Our research topics adopted by The Uehara Memorial Foundation

2016. 12. 15 Kazuki Urakawa awarded best poster presentation award  in 6 th. CSJ  Festa

                     (The Chemical Society of Japan).

                     Press release from Kumamoto University (Japanese)

2016. 11. 18  Our recent work published in Tetrahedron Letters

                      Acid-Mediated Aryl Migration Reaction of C3 Aryl Substituted Pyrrolidinoindolines

                      Shinji Tadano, Hayato Ishikawa*

                      Tetrahedron Lett. 58, 5–8 (2017).

2016.10.18  Our research topics adopted by Astellas Foundation for Research on Metabolic Disorders 

2016.10.17  Dr. Ishikawa awarded Research Achievement Award from Kumamoto University 2016

2016.10.17  Dr. Ishikawa awarded Chemist Award BCA 2016 from MSD Life Science Foundation

2016.9.29   update photos

2016.7.27  Kazuki Urakawa and his research introduced by Chem-Station (Japanease)

2016.7.7    Our research topics adopted by  TOBE MAKI Scholarship Foundation

2016.6.1    Prof. Pierre Mkounga (Yaounde I University, Cameroon) join to our group

                  as JSPS BRIDGE Fellow (long-term)

2016.5.13   Kazuki Urakawa awarded CSJ Presentation Award 2016 (The Chemical Society of Japan)

2016.5.4　 Our first material chemistry published in Angewandte Chemie, International Edition

　               Redox Switching of Orthoquinone-Containing Aromatic Compounds with Hydrogen and

                  Oxygen Gas

                  Kazuki Urakawa, Michinori Sumimoto, Mitsuhiro Arisawa, Masaki Matsuda*,

                  Hayato Ishikawa*

                 Angew. Chem., Int. Ed., 55, 7432–7436 (2016).

                 Press release from Kumamoto University (Japanese)

                 Press release from Kumamoto University (English)

　　　　     Symposium!

2016.4.1　New member join our group! update photos!

2016.2.1     Invited review article for Incentive Award in Synthetic Organic Chemistry Japan was

                   published.

                  Unified Total Synthesis of Tryptophan-based Dimeric Diketopiperazine Alkaloids.

                  Hayato Ishikawa

                  J. Syn. Org. Chem. Jpn., 74, 104–116 (2016).

2015.11.27 Our recent full paper published in Chem. Eur . J.

                   Collective Syntheses and Biological Evaluation of Tryptophan-based Dimeric

                   Diketopiperazine Alkaloids

                   Shinji Tadano, Yukihiro Sugimachi, Michinori Sumimoto, Sachiko Tsukamoto

                   Hayato Ishikawa*

                   Chem. Eur. J. 22, 1277－1291 (2016).

                   Selected “Hot Paper” and “Inside cover picture”

                   Alkaloids Synthesis using Chiral Secondary Amine Organocatalysts

                   Hayato Ishikawa*, Shinya Shiomi

                  Org. Biomol. Chem. 14,　409－424 (2016).

2015.11.1 Our research group awarded best promotion award in Science Festa 2015 for Students

                 （夢科学探検2015で優秀な展示をしたグループに送られる化血研賞を受賞しました！）

2015.9.3   Our recent work published in Chem. Eur. J.

                 Efficient Organocatalytic Construction of C4-Alkyl Substituted Piperidines and

　　　　   Their Application to Synthesis of (+)-α-Skytanthine

                 Shinya Shiomi, Erika Sugahara, Hayato Ishikawa*

                Chem. Eur. J., 21, 14758–14763 (2015).

Most accessed paper published in Chem. Eur. J. in Sep. 2015 ranked 3rd.

This research highlighted by Organic Chemistry Portal

2015.5.1   Shinya Shiomi awarded CSJ Presentation Award 2015 (The Chemical Society of Japan)

2015.4.1   New member join our group! update member and photo page.

2015.2.3　 update photo page.

2014.12.9    update invited lecture page.

2014.11.12   Erika Sugahara awarded poster presentation award  in 4 th. CSJ  Festa

                     (The Chemical Society of Japan).

2014.11.10　Dr. Ishikawa awarded Research Achievement Award from Kumamoto University 2014

2014.11.2.　 Visiting scientist Ms. Vina R. Aldilla (from Institut Teknologi Bandung, Indonesia)

                      join our group.

2014.8.9.　　Erika Sugahara awarded Poster Presentation Award for Excellence at

                      “51st Joint  Symposium of Chemistry Related Society in Kyushu Island”

                     （第51回　化学関連支部合同九州大会）

2014.04.01   New member join our group! update member and photo page.

2014.1.25     update Publication List and Presentation page

2013.12.6     Dr. Ishikawa awarded Incentive Award in Synthetic Organic Chemistry, Japan

2013.12.3     Dr. Ishikawa awarded Thieme Chemistry Journal Award 2014

2013.11.18　Dr. Ishikawa awarded Research Achievement Award from Kumamoto University 2013

2013.11.18  One-Pot Tamiflu synthesis was published in Chem. Eur. J.

                    One Pot Synthesis of (–)-Oseltamivir and Mechanistic Insights into the Organocatalytic

                    Michael Reaction

                    Takasuke Mukaiyama, Hayato Ishikawa, Hiroyuki Koshino, Yujiro Hayashi

                     Chem. Eur. J. 19, 17789 (2013).

                   Most Accessed Article 1/2013-12/2013; Ranked 8th.

2013.11.12  Rie Nakashima and Shinji Tadano awarded Poster presentation award

                     in 3rd. CSJ  (The Chemical Society of Japan) Festa, Japan.

2013.11.6  Our short review was published to Synlett (Invited Article as SYNPACTS)

                  Synthesis of Tryptophan-Based Dimeric Diketopiperazine Alkaloids Using Bioinspired

                  Reactions

                  Shinji Tadano, Hayato Ishikawa*

                  Synlett 25, 157-162, (2014).

2013.10.16　update photos and publication list

2013.6.21 Our first publication was published in Angewandte Chemie!!

    　          Bio-Inspired Dimerization Reaction of Tryptophan Derivatives in Aqueous Acidic Media:

                 Three-Step Syntheses of (+)-WIN 64821, (−)-Ditryptophenaline and (+)-Naseseazine B

                 Shinji Tadano, Yuri Mukaeda, Hayato Ishikawa*

                 Angew. Chem. Int., Ed. 52, 7990-7994 (2013).

2013.6.1　Shinji Tadano was awarded Poster Presentation Award for Excellence from SSOCJ

                  in 23rd Fukuoka Banyu Symposium, Fukuoka, Japan

2013. 5.25 Shinji Tadano was awarded Oral Presentation Award for Excellence

                  in 11th Organic Chemistry-the Next Generation, Tokyo, Japan

2013.4.1   New lab member join our group!

2013.2.1.  update Photos

2012.11.9. Shinji Tadano was awarded Oral & Poster Presentation Award for Excellence

                  in 102nd Symposium on Organic Synthesis, Japan

2012.7.20. update Photos

2012.5.24. Organocatalyzed Michael Addition of Aldehydes to Nitro Alkenes – Generally Accepted

                  Mechanism Revisited and Revised;

                  Most accessed paper published in Helvetica Chimica Acta from 2011 to 2012. Rank 1st.

2012.4.18. Our research group organize “Symposium of Natural Product Chemistry”

                   (July 4〜6 in Aso, Kumamoto);　

　　　　　第47回　天然物化学談話会を熊本で開催致します。（7月4〜6日、阿蘇）

2012. 4. 4. Our research group join to Scientific Research on Innovative Area, a MEXT Grant-In-

                  Aid Project ”Advanced Molecular Transformations by Organocatalysts”

2012. 4. 1.  New lab member join our group! up date Top, Member and Photos

2012. 3. 14. High-Yielding Synthesis of Anti-Infuluenza Neuraminidase Inhibitor (–)-Oeltamivir  by

                    Three “One-Pot” Operations;

                    Most cited paper published in Angew. Chem., Int. Ed. from 2009 to 2010. Rank 4th.

2012. 2012.2. 22. Our research topics adopted by The NOVARTIS Foundation (Japan) for  the
      

                     Promotion of Science

2012. 2. 20. Update Photos

2011.12.20. Our research topics adopted by UEHARA MEMORIAL FOUNDATION

2011.12.19. Dr. Ishikawa recieved IPSC 2011 Award

2011.12.2. Dr. Ishikawa recieved Eisai Award in Synthetic Organic Chemistry, Japan

2011.10.14. Our research topics adopted by THE NAITO FOUNDATION

2011.9.6. Our research topics adopted by JGC-S SCHOLARSHIP FOUNDATION

2011.8.30~31. Lab Camping in Yatsushiro; update Photos

2011.7.28. Update Top and Photos

2011.7.26. Update photos

2011.7.16.  Yuri Mukaeda join our group

2011.7.2~3. Lab Trip with Nishino Group in Amakusa; update Photos

2011. 2011.4. Our history just start !!